|
Symbol Name ID |
Shh
sonic hedgehog MGI:98297 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Ventricular septal defect |
Tetralogy of Fallot |
Abnormal pulmonary valve morphology |
Abnormal aortic morphology |
Arrhythmia |
Abnormality of the spleen |
| Disease(s) Associated with SHH | ||||||
| holoprosencephaly |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal cardiovascular system morphology |
abnormal artery morphology |
abnormal pulmonary artery morphology |
abnormal lung vasculature morphology |
abnormal physiological neovascularization |
abnormal vasculogenesis |
abnormal vascular smooth muscle morphology |
absent pulmonary vein |
abnormal atrium myocardium morphology |
abnormal cardiac outflow tract development |
persistent truncus arteriosus |
abnormal heart morphology |
abnormal heart left atrium morphology |
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| Availability | Mouse Genotype | ||||||||||||||
| Shhtm1(EGFP/cre)Cjt/Shhtm1(EGFP/cre)Cjt | |||||||||||||||
| Shhtm1Amc/Shhtm1Amc | |||||||||||||||
| Shhtm1Chg/Shhtm1Chg | |||||||||||||||
| Shhtm3(cre)Chg/Shhtm3(cre)Chg | |||||||||||||||
| Shhtm2Amc/Shhtm2Amc Tg(Atp4b-cre/ERT2)1Jrgo/0 (conditional) |
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| Shhtm1Chg/Shhtm2Amc Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
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| Shhtm1Chg/Shhtm2Chg Tg(Mef2c-cre)2Blk/0 (conditional) |
* | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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